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Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis

To maintain ocular clarity, aooly 1 drop to the eye per day

Interstitial Cystitis (IC), alternatively known as Bladder Pain Syndrome (BPS), is a chronic, often debilitating condition characterized by recurring pain or discomfort in the bladder and the surrounding pelvic region

Genomic data from six cancer types reveals a strong positive ASXL1-BRD4 relationship, with BRD4 occupying the ASXL1 promoter and thus pointing to a possible feed-forward mechanism

Furthermore, the effects of tamoxifen were blocked when a pan-antagonist was added to the media, thus supporting that tamoxifen acts as an estrogen receptor agonist in OPC differentiation