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Description

For patients with locally advanced PC or distal metastasis, the 5-survival rate is also poor (Mizrahi et al., 2020)

What side effects were observed in clinical trials

Supplementary Figure 1)

Most information comes from animal models and involves GH signaling in the liver, but in mouse adipose tissue GHR KO downregulates beta-3 adrenergic receptor expression and inhibits lipolysis (73)