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Experiments demonstrated that high levels of L-homocysteine and adenosine in the cell inhibit all methylation reactions

Hyperexcitability of individual neurons is another AD-linked phenotype, but we were unable to detect significant changes at the electrode level, again, likely due to the challenges of assigning effects to individual neurons with or without inclusions

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Plant Cell 23:364380 Sun W, Xu X, Zhu H, Liu A, Liu L, Li J, Hua X (2010) Comparative transcriptomic profiling of a salt-tolerant wild tomato species and a salt-sensitive tomato cultivar