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(1993) Insulin therapy increases low plasma growth hormone binding protein in children with new-onset type 1 diabetes

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This risk is heightened by genetic variants such as the OATP1B1 R57Q polymorphism, which impairs drug transport and can lead to systemic toxicity (62, 63)

TABLE 1 Roles of NOS isoforms in CRC: expression patterns, mechanisms, and therapeutic implications

This review demonstrated that compared with placebo interventions, probiotics, and other non-pharmacological treatments, acupuncture had a larger therapeutic effect on stool frequency, response rate, and had a lower rate of adverse events, providing some reasonable convincing evidence on acupuncture relatively ranked the best in managing CFC