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When those values are compared to the CRI calculated by Stephens for tobacco cigarettes (2.4 10 2 ), the ratio to cigarettes smoked CRI (15 cigarettes per day) to our results was found to be 3116.9 to 21818.2 times higher

But little is known about its toxicity when inhaled

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38 Unlike nicotine replacement therapy, the advertised nicotine dose on the labeling of e-cigarettes is not always consistent with laboratory analysis of the e-cigarette liquid, and the device and user behavior may affect the dose of nicotine received