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ChaC1 mRNA levels were markedly elevated in gastric cancer tissues treated with OP-B compared to adjacent normal tissues

Gu et al., 2014)

On-resin Alloc deprotection was achieved by addition of borane dimethylamine complex (14.7 mg, 0.250 mmol, 5.0 equiv.) and Pd(PPh 3 ) 4 (5.8 mg, 0.005 mmol, 0.1 equiv.) in anhydrous CH 2 Cl 2 (2.5 ml) to the resin (2 15 min, room temperature, with 2 4 ml of CH 2 Cl 2 wash in between deprotections)

(ii) near-neutral or lightly anionic surface chemistry and PEGylation extend circulation while reducing acute cationic toxicity