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American Association for Cancer Research:46, 2005

When 5-ALA is administered exogenously, one of its deriving porphyrinsprotoporphyrin IX (PpIX)preferentially accumulates in the intracellular compartment of tumor cells due to decreased levels of ferrochelatase and selective uptake by an ATP-binding cassette transporter (ABCB6) [120]

Rat Two- and eighteen-month-old adult lean SpragueDawley rats ( n = 12

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