slc25a39 is necessary for mitochondrial glutathione import in mammalian cells

slc25a39 is necessary for mitochondrial glutathione import in mammalian cells protein levels are directly regulated by cellular GSH SLC25A39 links mitochondrial GSH sensing

Name: slc25a39 is necessary for mitochondrial glutathione import in mammalian cells protein levels are directly regulated by cellular GSH SLC25A39 links mitochondrial GSH sensing
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SLC25A39 links mitochondrial GSH sensing with iron metabolism: Molecular Cell Mitochondrial GSH import is mediated by SLC25A39 a, Volcano plots Download Scientific Diagram Combinatorial GxGxE CRISPR screen identifies SLC25A39 in mitochondrial glutathione transport linking iron homeostasis to OXPHOS Nature Communications Autoregulatory control of mitochondrial glutathione homeostasis Science Mitochondrial Glutathione in Cellular Redox Homeostasis and Disease Manifestation

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The hypothesis has expanded to include vascular dysfunction, oxidative stress, microglial activation, and impaired proteolysis (Roda et al., 2022)

Occurrence Moreover, glutathione occurs in raw meat, fruit, and vegetables, while glutamine occurs in beef, pork, dairy products, raw spinach, raw parsley, and cabbage

An earlier study (Sikiric et al., 1993) confirmed the hepatoprotective effect using different liver injury models

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