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doi: 10.1016/j.freeradbiomed.2011.06.025

Thesis, University of Oregon, Eugene

Vitamin C: stimulates natural collagen production and provides clarity and vitality to the gaze

In vivo and in vitro studies have reported that EE itself is biotransformed for excretion mainly by glucuronidation (85%) and sulfation (12%) and that hydroxylation (mainly by CYP3A4 and CYP2A9 on C2) occurs only at low levels 22