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They exert pleiotropic effects, including modulation of oxidative stress, regulation of inflammatory pathways, and interference with oncogenic signalling cascades

Imperfect gold standards for biomarker evaluation

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It also nudges the skin toward making a lighter type of pigment instead of a darker one

69,80 During aging, the level of 2-microglobulin (a component of major histocompatibility complex (MHC)-I) in plasma increases, leading to a proinflammatory phenotype in monocytes, cognitive decline, and regenerative impairments in the adult brain