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In this way, HIV-infection itself if left untreated has been shown to convert the immune system of a young individual into one similar to someone 40 years older (Ferrando-Martnez et al., 2011)

Hall MG, Ferrell WR, Sturrock RD, Hamblen DL, Baxendale RH

doi: 10.1038/s41598-019-43849-5 74 aniewskiP.Herbst-KralovetzM

Ethics declarations Funding Declaration The authors declare that no funds, grants or other support were received during the preparation of this manuscript

Nanogels, featuring high mucoadhesion and sustained release profiles (e.g., chitosan/alginate gels achieving 5-day release), enhance localized therapeutic efficacy when integrated with functional materials like carbon nanosponges (Niu et al., 2023