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3.2.3 Neuroinflammatory imaging in Parkinsons disease Rats overexpressing mutant -synuclein exhibit early, region-specific ([18F]DPA714) binding increases in the substantia nigra and striatum prior to overt dopaminergic neuron loss and motor deficits, indicating that PET-detected microglial activation anticipates classical PD pathology (146)

Additionally, the corpus callosum is a well-documented region of demyelination in CPZ and LPC in vivo models and is affected in MS patients (Steelman et al., 2012

This is why its crucial to ensure peptides come from reputable sources or pharmacies that adhere to strict quality control standards, ensuring the product is both safe and effective

J Clin Invest (2018) 128:344559

Contaminated, mislabeled, or adulterated products could cause harm that has nothing to do with the peptide itself