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These data demonstrate that metformin alters metabolism, specifically inhibiting oxidative phosphorylation, and induces significant mitochondrial dysfunction in both HCT116 and SW837 cells, supporting its metabolic modulatory effects in CRC in vitro

Association between increased and decreased gut microbiota abundance and Parkinsons disease: a systematic review and subgroup meta-analysis

More than just alcohol that we drink: In addition to the beer, wine, and other alcohol we might drink, the alcohol dehydrogenase enzyme also breaks down alcohols produced by bacterial fermentation in the intestines

Micali N, Chakrabarti S, Fombonne E

Excessive glutamate signaling can induce neuronal dysfunction and cell death through the production of excitotoxicity, a process characterized by a large influx of calcium, which results in a cascade of events involving the disruption of calcium-dependent cellular pathways, mitochondrial dysfunction, the production of oxidative stress, and the activation of apoptosis