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For instance, some studies have failed to show any benefit of L-carnitine supplementation on outcomes such as the incidence of heart failure or myocardial reinfarction (CEDIM-2 trial)

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Certain immunosuppressants administered following liver transplant have been implicated in IBD worsening, specifically tacrolimus [228, 229] and tacrolimus-based regimens, such as tacrolimus and mycophenolate mofetil [230]

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