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Melanocytes can also function as neuroendocrine cells by producing acetylcholine, catecholamines, and POMC-derived peptides, which have the capacity to mediate local immunoinflammatory and antimicrobial responses and to modulate the biological behaviour of oral tissues [4]

Multiple lesions may be a sign of a widespread skin condition, such as: A melanotic macule has a characteristic pattern when examined with the magnifying glass or by dermoscopy

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First Atlanta, then Boulder: Two mass shootings in a week, New York Times, March 23