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Before being peroxidized, PUFAs are thioesterified by acyl-CoA synthetase long-chain family member 4 (ACSL4) and then combined with phospholipids to integrate into the plasma membrane by lysophosphatidylcholine acyltransferase 3 (LPCAT3), finally polyunsaturated fatty acyl moieties present on phospholipids (PL-PUFAs) are formed

The presence of extra-synaptic NMDA currents directly depends on astrocytes intracellular Ca 2+ concentrations

In vivo denervation experiments C57BL/6 or Sox2eGFP mice were administered with analgesics 30 min prior to surgery (carprofen and buprenorphine

Mutations in CFTR, which form the basis for the clinical manifestations of cystic fibrosis, affect the epithelial innate immune function in the lung, resulting in exaggerated and ineffective airway inflammation that fails to eradicate pulmonary pathogens

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