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It is an enzyme that turns male hormone T into dihydroT

Cysteine depletion, which results in the intracellular exhaustion of glutathione, serves as a preliminary feature of the mechanism and triggers ferroptosis ( The biological features of ferroptosis are distinguished by the aggregation of iron and ROS, which reduces the level of cystine uptake and consumes GSH to inhibit the activities of system xc- and GPX4

Fan X, Liu H, Liu M, Wang Y, Qiu L, Cui Y