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Conversely, NEDD4 binding protein 3 (N4BP3) exacerbates the inflammatory response by facilitating K63-linked ubiquitination of RIPK2, suggesting that regulating RIPK2 ubiquitination status may also serve as a potential therapeutic target [466,467,468]

More blood flow means more nutrients and faster healing in cartilage and connective tissues

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Woreta, Johns Hopkins Medicine, Baltimore, MD and Saleh A Alqahtani, Johns Hopkins University School of Medicine