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Mechanistically, circEZH2 upregulates KLF5 expression by sponging miR-217-5p to promote tumorigenesis and metastasis

Boewe AS, Wrublewsky S, Hoppstdter J, Gtz C, Kiemer AK, Menger MD, et al

10.1024/0300-9831/a000493 142 XuQ.LangleyM.KanthasamyA

Furthermore, the inhibition of selenoproteins by MG and its effect on GSH metabolism provide a potential molecular mechanism for its ferroptotic activity, which is a key factor in the progression of kidney injury