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10.1101/gr.10.4.403 Genome Res

[15] Although a large burst of ROS is known to lead to cell damage, a moderate release of ROS from the mitochondria, which occurs during nonlethal short episodes of ischemia, can play a significant triggering role in the signal transduction pathways of ischemic preconditioning leading to reduction of cell damage

The groups were matched to the best of the researchers abilities, given the limited sample size, and the study was performed in a double-blind crossover manner with a one week washout period

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10.3390/ijms23116196 108