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Genome-wide profiling of DNA methylation reveals transposon targets of CHROMOMETHYLASE3

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Antioxidants 9, 700722

Timothy R

Under stress such as amino acid deprivation or oxidative condition, NRF2 migrates to the nucleus to initiate transcription of the antioxidant response element (ARE)-containing genes via disassociation from KEAP1 [78]

Given the central role of ROS homeostasis in health and disease, targeting ROS and their mediated ROS balancing pathways holds great therapeutic potential [556, 557]