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FBXL5 depletion in DC2.4 cells was achieved using a lentiviral CRISPR-Cas9 system followed by puromycin selection

Additionally, oral semaglutide is currently approved for the treatment of T2DM

Cagrilintide (Cagri), functioning as a dual amylin receptor (AMYRs) and calcitonin receptor (CTR) agonist (DACRA), demonstrates significant efficacy in obesity treatment, although its structural activation mechanism remains unclear