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Nucleic Acids Res 49:W388W396 Peterson LW, Artis D (2014) Intestinal epithelial cells: regulators of barrier function and immune homeostasis

Notably, the exact mechanism of action for each therapeutic is not known

Additionally, inhibiting -KG dehydrogenase enhances -KG levels and TET activities, restoring DNA demethylation and ameliorating the progression of T2DM and breast cancer