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Its often caused by an excess of androgens, male hormones like testosterone, or increased sensitivity of hair follicles to normal androgen levels

Building on these findings, future studies will focus on in vivo pharmacokinetic and pharmacodynamic profiling to validate EV-QuerCars antioxidant and anti-aging efficacy in preclinical models, including biodistribution, sustained release kinetics, and systemic toxicity assessments

The dosage of Cur + CDDP was equivalent to the individual dosages of Cur and CDDP

Nevertheless, further validation in larger clinical cohorts is required before such an approach can be broadly implemented

Butyrate ameliorated ferroptosis in ulcerative colitis through modulating Nrf2/GPX4 signal pathway and improving intestinal barrier