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Ming et al

However, the approach carries risks

LPS crosses through intestinal cells, triggering mast cell activation

Payer contracts don't adjust upward automatically

19, 20 Prevalence The widely cited prevalence figure of 1:30,000 for WD with a heterozyogous ATP7B mutation carrier frequency of 1:90 was estimated in 1984 and thus predates the identification of ATP7B as the causative WD gene