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Nonetheless, ADI-cell penetrating fusion protein complex, arginase-fc protein and ADC require further investigation for the efficacies in arginine depletion cancer therapy

It differs significantly from traditional apoptosis, pyroptosis, and necrosis ( 2.2.1 Lipid peroxidation and Fenton reactions Lipid peroxidation is the core molecular event in ferroptosis ( 2.2.2 Glutathione Peroxidase 4 (GPX4) and its role in ferroptosis GPX4 is a selenoprotein that plays a central role in suppressing ferroptosis by catalyzing the reduction of membrane-bound phospholipid hydroperoxides (PL-OOH) into their corresponding non-toxic alcohols (PL-OH), thereby preserving lipid bilayer integrity under oxidative stress ( Beyond its classical enzymatic role, GPX4 is subject to multifaceted regulation

If the folate trap is avoided, we may not have signs of B12 deficiency anemia

Supports collagen production and improves skin elasticity

CXCL10 antibody injection significantly restored the number of follicles at each stage (Fig