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They define PCOS as the presence of two out of three criteria: hyperandrogenism (elevated levels of male hormones, assessed clinically -presence of acne, hirsutism- or biochemically), ovulatory dysfunction (oligo/anovulation, infrequent or absent ovulation), and/or polycystic ovarian morphology on ultrasound: either the presence of 20 or more follicles on a single ovary or ovarian volume above 10 cm3

8 The symptoms exhibited in rebound withdrawal are understudied and can vary greatly from individual to individual

The remarkable findings by Ito et al

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Falkai P, Raabe F, Bogerts B, Schneider-Axmann T, Malchow B, Tatsch L, et al