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The ATP-depleting futile 5-oxoproline cycle may also play an important role in other acetaminophen toxicity syndromes related to ATP depletion

The study results showed improved dermal density, skin texture, and reduced wrinkles for all the treatment groups tested

Chemical Research In Toxicology 1997, 10: 875-879

Vetter, Loss of fractalkine signaling exacerbates axon transport dysfunction in a chronic model of glaucoma

Main reasons for changes in therapy are side-effects and insufficient therapy response, which highlight the importance of regular follow-up and screening for side-effects