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In the present study, we established a rat model of -cell failure using LOsG and found that high glucose promoted PSC activation and proliferation to enhance pancreatic fibrosis

As a consequence of these observations, our results suggest that autophagy may be an adaptive response to continuous metabolic alterations and that its induction may result in a protective attempt to antagonize degenerative processes and to enhance survival in normal appearing vitiligo skin, where melanocytes and fibroblasts are already prone to premature senescence

Notably, probiotics have shown considerable promise in reducing the incidence of certain cancers, especially colorectal and bladder cancer (296, 297)

Mercapturic acid biosynthesis of 1-Chloro-2,4-dinitrobenzene in Rat Kidney