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D.McKinneyJ

Signs of B12 Deficiency to Watch For Breastfeeding mothers should be aware of symptoms that may indicate a B12 deficiency, such as persistent fatigue, weakness, tingling in the hands or feet, memory problems, or mood changes

Foods, 11 (15), 2189

The Pyruvate Dehydrogenase complex oxidizes pyruvate produced by glycolysis to acetyl-CoA, and is a major control point of TCA cycle activity for carbohydrate metabolism (Gray, Tompkins, & Taylor, 2014)