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It functions as the primary intracellular antioxidant, donating electrons to neutralise reactive oxygen species (ROS) produced during mitochondrial respiration and inflammatory processes

Barry Conrad It's going to be a bit, one thing I know is if this were happening in reality, Mel, as always, we'll have a big table and the people would say, but it's just the two of you, I'm like, we know

PARK7 interacts with alpha-synuclein, a protein that is found in clumps (Lewy bodies) in the brains of people with Parkinsons disease

whether fumarate directly modifies GPX4 or acts via other succination targets to drive ferroptosis is unclear

Seiwerth, S., et al