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It is frequent and may lead to treatment failure due to poor adherence to the prescribed treatment

Nat Commun (2019) 10(1):118

10.1016/j.bbmt.2011.11.029 8 GongF.HuH.OuyangY.LiaoZ

127 SFAs, such as palmitic acid, can increase the production of ceramide and NO, leading to impaired insulin synthesis, and the apoptosis of cells through inflammation, ERS, and oxidative stress, which can be blocked by unsaturated fatty acids