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While the roles of neurotransmitters are dynamic, and can switch depending on age and circumstance, the fact that neurotransmitter classes are well-elucidated, and we are learning more and more about their contributions to health and disease, creates optimism that we can uncover the molecular mechanism(s) of neurostimulation

5 Stem cells in intervertebral disc repair The most important pathological features of IVDD include metabolic imbalance of proteoglycans and type II collagen in the extracellular matrix (ECM), and a reduction in the number of nucleus pulposus cells (NPCs) (Xin et al., 2022)

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