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2016;12(9):e1005821

doi: 10.1056/NEJMoa2204705 177 MindellJ

In humans, Menkes syndrome is a main manifestation of copper deficiency and causes serious neurological disorders (Danks et al., 1972

Activated LINE elements generate abundant RNADNA hybrids, which are recognized as foreign nucleic acid signals by the cGAS-STING pathway, inducing immune responses and amplifying inflammatory signals closely linked to neuroinflammation in AD