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Through using the methods of the invention, one can obtain agonists or antagonists that avoid these potential drawbacks

Interspecies scaling (for example, body-surface-area conversion) typically reduces a rodent mg/kg figure severalfold, and even a properly scaled number would still be a hypothetical exposure , not a validated dose

For instance, MERS-CoV first caused an epidemic in humans after zoonotic transmission in 2012, although serological evidence suggests that it had been circulating in dromedary camels since the 1980s

Its stability and consistent quality have made it a trusted choice for research laboratories

doi: 10.1016/j.expneurol.2014.04.017, PMID: [DOI] [PubMed] [Google Scholar] 78.Dbek A, Wojtala M, Pirola L, Balcerczyk A