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These opposite results may partly attributed to colonization at birth, age, gender, diet, and other factors (Gilbert et al., 2018)

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Patients frequently describe a profound, crushing fatigue that does not improve with rest, accompanied by a thick, disorienting cognitive impairment commonly referred to as "brain fog." For those living with these invisible illnesses, the frustration of navigating a medical system that often lacks clear answers can be just as exhausting as the physical symptoms themselves

doi: 10.3389/fonc.2020.00409 96 DingW-QLindSE

Nature 486 , 532536 (2012)