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Originally developed in the 1990s, as a fat burning (lipolytic) compound, AOD9604 stimulates the breakdown or destruction of fat cells (lipolysis) and inhibits the metabolic formation of fat (lipogenesis) in animal studies

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Assuming the extent of absorption of imiquimod through the oral mucosa is similar to that of the dermis (~ 0.6% per application and terminal half-life of 20 hours) (41), the smaller dose used in our study compared to that recommended for skin cancer may have contributed to a lack of more serious systemic adverse events, such as flu-like symptoms