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Bioengineered 12(2):1092410934 Ghiasian M, Khamisabadi F, Kheiripour N, Karami M, Haddadi R, Ghaleiha A, Taghvaei B, Oliaie SS, Salehi M, Samadi P, Ranjbar A (2019) Effects of crocin in reducing DNA damage, inflammation, and oxidative stress in multiple sclerosis patients: a double-blind, randomized, and placebocontrolled trial

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Autophagy is involved in synaptic homeostasis and regulation of neurotransmitters, thus defective autophagy is linked with a reduction in the activity of certain neurotransmitters mainly GABAergic neurotransmitters (Yin et al

B Vitamins and Energy Production B Vitamins act as coenzymes that facilitate the conversion of macronutrients (carbohydrates, fats and proteins) into usable energy

Astrocytes are highly responsive glial cells that interact with immune and neural cells and become activated when encountered with any foreign insult, including chronic injuries, infections, acute trauma and neurodegenerative diseases 20