organic halide glutathione Glutathione-Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation Horbaach L Glutathione Complex | Martin's Wellness

Abcam, 1:200 dilution) and fluorescent secondary antibodies (Alexa Fluor series, Invitrogen) for visualization

Jul-Aug 2015;81(4):347-51

It helps protect cells from oxidative stress, supports detoxification pathways and helps recycle other antioxidants

Genes Dev 13:7686

CER is able to regulate iron metabolism levels in HCC cells to modulate iron toxicity, and when protein levels are reduced, It leads to increased intracellular iron levels and accumulation of lipid peroxides, Then promotes erastin and RSL3-induced iron toxicity, which may be achieved by relying on FPN, The inhibitory effect of CER on ferroptosis was abolished when FPN expression was inhibited by shRNA [154]