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Eur J Immunol (2011) 41(3):86372.10.1002/eji.201040649 48 LiHFuYXWuQZhouYCrossmanDKYangPet alInterferon-induced mechanosensing defects impede apoptotic cell clearance in lupus

Gut microbiota dysbiosis and metabolites (e.g., histamine, SCFAs) modulate visceral sensitivity and low-grade inflammation, affecting bowel motility, sensitivity and secretion