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Patients with autistic spectrum disorders (ASDs) exhibit higher proportions of mitochondrial dysfunctions than the general population (Rossignol and Frye, 2012), as evidenced by developmental regression, seizures, and elevated serum levels of lactate or pyruvate in ASD patients

To view or add a comment, sign in FDA Approval Update The FDA has approved Sarclisa Escena (isatuximab-irfc) from Sanofi as a subcutaneous formulation of isatuximab for approved multiple myeloma treatment combinations

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Under basal, unstressed conditions, their levels are kept low due to targeted degradation by the proteasome

M., Bhunia, A