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While the dominant penta-acylated lipid A in Bacteroidetes does not elicit an interferon IFN- response, the less abundant tetra-acylated lipid A induces IFN- sustainably and so contributes to homeostasis of Treg cells and a healthy immune system

Frye received grant support from Assurex Health, Baszucki Group, Myriad, Mayo Foundation and BD2, received CME travel and honoraria from Carnot Laboratories and American Physician Institute and has Financial Interest/Stock ownership/Royalties from Chymia LLC

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This is the practical way to avoid undersized or oversized systems later on