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Third, the translation of ferroptosis research achievements into clinical therapeutic modalities necessitates overcoming formidable barriers related to drug delivery, dose optimization, and efficacy evaluation

Cell 150 , 883894 (2012)

The molecules can easily adsorb on the AuNP surface by thiolation, chemical modification using chemistries such as 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC), streptavidin/biotin binding [3, 124,125,126,127] and ionic interactions based on opposite charges between the NP surface and the biomolecules [124,125,126]