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For patients who are newer to peptide therapy, older patients whose pituitary GH output has declined significantly with age, or those who prefer a more conservative starting protocol, Sermorelin is an excellent foundational choice before transitioning to the more potent CJC-1295/Ipamorelin stack

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How long this lasts depends on how well the patient responds and the severity of the deficiency

Massage improves distribution and may enhance penetration through mechanical action

However, they work in different ways in the body