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These compounds, in the course of their auto-oxidation, produce free radicals, which in turn oxidize GSH and thereby activate the chain reaction of events previously outlined

Its 44-amino acid sequence closely mirrors endogenous GHRH(1-44), but the trans-3-hexenoic acid modification at the N-terminus confers resistance to dipeptidyl peptidase-IV (DPP-IV) cleavage, extending its biological half-life

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[DOI] [Google Scholar] 163.Franzago M., Borrelli P., Di Nicola M., Cavallo P., DAdamo E., Di Tizio L., Gazzolo D., Stuppia L., Vitacolonna E