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Description

Reportedly, Meldonium lowers the production of TMA by inhibiting the L-carnitine metabolism intermediate -butyl betaine (83)

At 70 mg/kg, which is the recommended dose in acute cyanide poisoning, the elimination half-life was 7.36 +/- 0.79 h, the volume of distribution was 0.49 +/- 0.10 L/kg, and the total clearance 0.58 +/- 0.11 L/h