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Nevertheless, a large study (n=646) from Japan in patients with decompensated cirrhosis of mixed etiology has shown reduction in episodes of decompensation or mortality over 2 years using a diet supplemented with 1.01.4 g protein/kg/d, BCAA and 2535 kcal/kg/d

These changes in morphology towards a more quiescent phenotype were accompanied by a reduction in production of proinflammatory cytokines and mediators

Feeding diabetes-prone BioBreeding (BBdp) rats a hydrolyzed casein-based diet, a diet that binds nutritional copper and lowers tissue copper, promotes islet cell neogenesis and results in 23-fold fewer diabetes cases compared with feeding cereal-based diets [ 43 ]