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For example, glucose is the main substrate that photoreceptors utilize to create ATP in vivo 12 , but they can oxidize lipids, lactate, and use amino acids, fatty acids (such as palmitate) and other intermediate substrates to produce ATP, especially under glucose-deprived conditions 10,11,12

At this juncture, one might consider whether the glucose catabolic pathway harbors exploitable vulnerabilities

It also matters if you have surgery planned or severe GI symptoms

Antitumor immune cells appear to promote tumor cell ferroptosis, while immunosuppressive cells and adipocytes inhibit it, collectively influencing tumor fate (69)

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