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Its symptoms may include problems with memory, spatial awareness, focus, and cognitive functions

Among these late effects, organ fibrosis is the most prevalent and can cause significant damage

Among the intrinsic factors are the sirtuins (SIRTs), a family of NAD + -dependent lysine deacetylases, some of which are exclusively expressed in mitochondria (SIRTs 3, 4, and 5) (Mattes et al., 2019)