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Blood samples were obtained from the mice every two to four weeks in order to estimate antibody titer, virus neutralization assays, and ACE2 binding inhibition

PMID: 36556267

Specifically, one study reported an average weight loss of 20.4% after 68 weeks, compared to only 3% in those not using the treatment

That 23-pound difference represents meaningful additional risk reduction for obesity-related conditions

Commonly reported observations include: Reduced joint stiffness, particularly morning stiffness Improved range of motion in affected joints Decreased reliance on anti-inflammatory medications Better tolerance of physical activity and exercise These clinical observations are valuable but represent anecdotal evidence